Novel Innovations Pushing the Potential of Determining Antibiotic Susceptibility

The performance of antibiotic susceptibility testing is a significant task in clinical microbiology laboratories, where the goal is to detect potential drug resistance in pathogens and determine their susceptibility to antibiotic drugs. Rapidly automated instrument or broth microdilution methods are the most widely used antibiotic susceptibility testing methods. Although the present methods for antibiotic susceptibility testing provide accurate detection, the newer and emerging methods are expected to raise the bar of detection and determination of antibiotic susceptibility testing.

Moreover, the arising issue of antibiotic resistance has witnessed tremendous growth globally. The new and emerging resistance mechanisms are spreading rapidly and threatening the ability to treat infectious diseases. According to WHO, antibiotic resistance is currently amongst the biggest threats to global health, development, and food security. Such scenarios are creating the need for improved antibiotic susceptibility testing solutions.

Revolutionary Developments Make Way towards Quick-paced and Accurate Testing

There is an accelerating growth witnessed by the microbiology study, which has triggered major research and development that aims to boost the overall capabilities of modern microbial testing. Antibiotic susceptibility testing has witnessed tremendous growth with the rapid integration of technology and the accuracy achieved by the introduction of new methods and systems for antibiotic susceptibility testing. Technological enhancements along with the continual research are together contributing to better, faster, and effective antibiotic susceptibility testing.

A team of expert researchers at the Baptist University based in Hong Kong have progressed in the same line with the development of a relatively cost-effective and accurate method for antibiotic susceptibility testing method. This new method for antibiotic susceptibility testing is claimed to cost at half the price and deliver 10 to 20 times faster results compared to the existing antibiotic susceptibility testing methods. Furthermore, the new invention in antibiotic susceptibility testing is said to reduce the problems of misuse and abuse of antibiotics, enabling end-users to obtain better estimations pertaining to the drug efficacy.

Similarly, the scientists at GeneCapture, Inc., a developer of diagnostic devices for pathogen identification and detection, on the HudsonAlpha Institute for Biotechnology campus working on a new method to report the phenotypic antibiotic resistance, directly from the samples collected from patients within 5 to 75 minutes. Being designed for the emergency and point of care application, this new rapid antimicrobial susceptibility testing method. While the current antibiotic susceptibility testing takes few days to determine antibiotic susceptibility and identify pathogens, the GeneCapture’s platform would complete identification in about 45 minutes.

New Initiatives Aimed at Tackling Global Health Crisis: Antibiotic Resistance

The increasing issues pertaining to the antibiotic resistance of the pathogens has sent across storming concerns through global economies. The scientific community is working to address these challenges by developing new and effective diagnostic technology and antibiotic drugs for better identification of resistant microbes. Investments remain a crucial aspect for the growth of new testing methods in the healthcare sector. Scientists and researchers working in boosting the potential of antibiotic susceptibility testing are benefitting from the increasing investments.

Solutions such as antibiotic susceptibility testing could help mitigate the global crisis of antibiotic resistance. In the wake of the increasing concerns of antibiotic resistance, the National Institutes of Health (NIH) has extended a grant of about $5.8 million to the Biodesign Center for Immunotherapy, Vaccines and Virotherapy and the School of Life Sciences, for the development of a more effective antibiotic susceptibility testing solution, which could not identify bacterial cells and determine their antibiotic susceptibility.

Collaborations and partnerships are also witnessed in the antibiotic susceptibility testing landscape. Symcel, a provider of cell-based technology entered into a partnership agreement with Karolinska Institutet, for validating and verifying the cell-based assay tool by Symcel, calScreener in the antibiotic susceptibility testing. This tool is developed for real-time cell metabolism measurement and it was to be examined for its capability of testing the efficacy of several antibiotic combinations that work against drug-resistant bacteria.

There are several opportunities held by the antibiotic susceptibility testing ecosystem over the forthcoming years. A detailed market research study on the antibiotic susceptibility testing market offers a significant overview of the potential scope that antibiotic susceptibility testing providers could leverage from.

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